Biphenotypic, bilineal, ambiguous or mixed lineage: strange leukemias!
نویسنده
چکیده
منابع مشابه
Lineage ambiguity, infidelity, and promiscuity in immunophenotypically complex acute leukemias: genetic and morphologic correlates.
The laboratory characterization of acute leukemia has evolved as new technologies have emerged and been applied in the routine evaluation of these hematologic malignancies. With the use of morphology, cytochemistry, flow cytometry, cytogenetics, and molecular genetics, it is possible to characterize acute leukemias in an extremely sophisticated and (ideally) therapeutically rational manner. Suc...
متن کاملMixed-phenotype acute leukemia (MPAL) and beyond
which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited. Mixed-phenotype acute leukemia (MPAL) is a rare but difficult to treat hematologic malignancy with immuno-phenotypic co-expression of at least two cell lineages, or with only rare cases involving all three lineages, e.g. myeloid with B-or T-lymphoid or all t...
متن کاملOccurrence of the Common Acute Lymphoblastic Leukemia Antigen on Blast Cells of a Patient with Chronic Myelomonocytic Leukemia in Non - Lymphoid
Leukemias showing a conspicious lymphoid phenotype. ie. those that are HLA-DR positive. common acute lymphoblastic antigen (cALLA) positive. terminal deoxynucleotidyl transferase (TdT) negative, as well as myeloperoxidase positive (MPO). could be considered so-called mixed leukemias. Leukemias with biphenotypic blasts have to be distinguished from cases comprising two separate subpopulations th...
متن کاملOccurrence of the Common Acute Lymphoblastic Leukemia Antigen on Blast Cells
Leukemias showing a conspicious lymphoid phenotype. ie. those that are HLA-DR positive. common acute lymphoblastic antigen (cALLA) positive. terminal deoxynucleotidyl transferase (TdT) negative, as well as myeloperoxidase positive (MPO). could be considered so-called mixed leukemias. Leukemias with biphenotypic blasts have to be distinguished from cases comprising two separate subpopulations th...
متن کاملImmunocytochemical markers in acute leukaemias diagnosis.
The study included 1742 patients with acute myeloblastic leukaemias (AML) and acute lymphoblastic leukaemias (ALL), Kyiv city residents and patients from 20 regions of Ukraine. Bone marrow and blood smears were sent at diagnosis to Reference Center. The analysis was based on May-Grünvald-Giemza (MGG) stain and cytochemical reactions (MPO, acNSE, CAE, AP, PAS). Immunocytochemical techniques (APA...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
عنوان ژورنال:
- Haematologica
دوره 94 7 شماره
صفحات -
تاریخ انتشار 2009